Hypoosmotic Swelling (HOS) Assay

December 23, 2008 at 10:09 pm · Filed under andrology, science, semen analysis, sperm testing

Hypoosmotic Swelling (HOS) Assay

Sperm with a physically intact and functionally active membrane will respond to changes in osmolality. This property of the sperm is utilized in the HOS assay which has been shown to correlate highly with the ability of sperm to fertilize intact human oocytes in vitro. It also appears to predict in vitro fertilizing capacity of spermatozoa more reliably than the standard sperm parameters.

Dr S

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